Siegfried O Schmidt, MD, PhD

Ongoing Research Support Co-Investigator for “Pharmacokinetic and Pharmacodynamic (PK-PD) Studies of Cardiovascular Drugs” (Source: 1U01FD005235-01) PIs: L.Cavallari and J.Johnson. PK-PD study is sponsored by the Food and Drug Administration (FDA) for a total award $ 2,332,870. University of Florida, Gainesville, Florida, September 1, 2014 through August 31, 2017 PI for “Establishing a Pain Management Program within a University based Family Medicine Residency.” (IRB Project 2014 01037), University of Florida, Gainesville, Florida, May 22, 2015 through May 22, 2020. Completed Support Sub-Investigator for “Implementing Genomics in Practice (IGNITE) Proof of Concept Study: Genotyping in Family Medicine Clinics.” PIs: L. Cavallari, PharmD, and J Johnson, PharmD, Genomic Medicine Implementation: The Personalized Medicine Program, University of Florida Health. University of Florida, Gainesville, Florida, March 4, 2015- September 1, 2016. Co-Investigator for “An Integrative and Sustainable Approach to Pain Management in Primary Care” (UF Project #108663, UF Contract #89684. Sponsored by a Pfizer. 07/01/2013 thru 06/30/2015 Sub-Investigator for “Pharmacogenomic Evaluation of Antihypertensive Responses II (PEAR) grant project; Julie A. Johnson PharmD, Principal Investigator. The PEAR grant is sponsored by the National Institutes of Health for a total award $ 2,064,000. University of Florida, Gainesville, Florida, 2010 – 2013.

Sub-Investigator for “Antihypertensive Medication Exposure as Risk for Impaired Glucose Tolerance: A PEAR Sub-Study (#237-2009). PEAR Extension Study project. Julie A. Johnson PharmD, Principle Investigator, Supervisory Chair of Graduate Committee, Rhonda Cooper-DeHoff PharmD, Co-Principle Investigator, Graduate Committee Member, Mariellen J. Moore PharmD, Sub-Investigator, Graduate Student, Whit Curry MD, Sub-Investigator, Kendall Campbell MD, Sub-Investigator, John Gums PharmD, Sub-Investigator. The PEAR grant is sponsored by the National Institutes of Health. University of Florida, Gainesville, Florida, 2009 – 2012.

Sub-Investigator for “Atenolol exposure as risk for adverse metabolic responses to beta blockers”. PEAR extension study project; Julie A. Johnson PharmD, Principal Investigator. The PEAR grant is sponsored by the National Institutes of Health for a total award $205,992University of Florida, Gainesville, Florida, 2007 – 2012. Sub-Investigator for “Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) grant project; Julie A. Johnson PharmD, Principal Investigator. The PEAR grant is sponsored by the National Institutes of Health for a total award $ 205,992. University of Florida, Gainesville, Florida, 2005 – 2010.

Sub-Investigator for “Characteristics of Central Pain Sensitization in Chronic Pain Diseases Following Analgesic Intervention,” Principle Investigator A.P. Mauderli, University of Florida, Gainesville, Florida, 2005 – 2012. Sub-Investigator for “Spatial and Temporal Characteristics of Central Pain Sensitization in Chronic Pain Diseases,” Principle Investigator A.P. Mauderli, funded by the BSCIRTF Research Program of the McKnight Brain Institute, University of Florida, Gainesville, Florida, 2005 – 2010.

“Helping Educators Address the Development of Appropriate Curriculum for Headache Education (HEADACHE) Project.” Curriculum Committee Member and Consulting Faculty. The HEADACHE project is sponsored by the National Headache Foundation (NHF), in cooperation with the Society of Teachers of Family Medicine (STFM), 2003 – 2006.

Sub-Investigator for “Central Pain Sensitization in Irritable Bowel Syndrome.” Principle investigators: G.N. Verne and A.P. Mauderli, sponsored by National Institute of Health HINDS and Research Service of the Veterans Administration, Gainesville, Florida, 2003 – 2004.

Principle Investigator for “Ongoing Effectiveness of a Diabetes Flow Sheet in Improving Diabetes Care in Family Practice,” Protocal 33-2003, University of Florida, Gainesville, Florida, 2003 – 2004.

Sub-Investigator for “Residency Training in Primary Care Grant,” To better teach residents end-of-life care. Principle investigator: K Hall, sponsored by HRSA, 2002 – 2005.

Sub-Investigator for “The Effect of Mild Traumatic Brain Injury on Pain Perception in Human,” Protocol 465-2002. Principle Investigator A.P. Mauderli, funded by the BSCIRTF Research Program of the McKnight Brain Institute, University of Florida, Gainesville, Florida, 2002 – 2006.

Sub-Investigator for the INVEST Sub-study, “Heart Disease Outcomes: Impact of Genetics and Pharmacogenetics,” Protocol 661-00. Principal Investigator C.J. Pepine, University of Florida, Gainesville, Florida, 2002 – 2005.

Co-Investigator for the National Institutes of Health grant “Spatial and Temporal Characteristics of Central Pain Sensitization in Chronic Pain Diseases,” Principle Investigator A. P. Mauderli; University of Florida, Gainesville, Florida, 2002 – 2012.

“ASTHMA COLLABORATIVE,” a Learning and Improvement Collaborative on Healthcare for Children with Asthma. This was a quality improvement project developed and facilitated by the National Initiative for Children’s Healthcare Quality (NICHQ), and was sponsored by AAFP (American Academy of Family Physicians) as part of their Quality Initiative. Participated as a team member, Quality Care Committee, Department of Community Health and Family Medicine, University of Florida, Gainesville, Florida, 2002 – 2003.

Co-Project Director for the HRSA grant, “Establishment of Departments of Family Medicine, 93,984”, “Family Medicine Quality Improvement Initiative” at the University of Florida, Gainesville, Florida. Fund amount: $250,526, 1999 – 2002.

Sub- Investigator for Invest Study (International Verapamil SR-Trandolapril Study), University of Florida, College of Medicine, Gainesville, Florida, 1997 – 2003.