William Friedman, M.D.

William A Friedman, M.D.

(352) 273-6990

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Publications

Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas
American Journal of Clinical Oncology-Cancer Clinical Trials
2018

A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence.
Cell Reports
2018

The risk of malignancy anywhere in the body after linear accelerator (LINAC) stereotactic radiosurgery
Stereotactic and Functional Neurosurgery
2014

The Accuracy of Predicting Survival in Individual Patients With Cancer
Journal of Neurosurgery
2014

Readmissions in Neurosurgery: a Qualitative Inquiry
World Neurosurgery
2014

The Somatic Genomic Landscape of Glioblastoma
Cell
2013

Stereotactic Radiosurgery of Intracranial Arteriovenous Malformations
Neurosurgery Clinics of North America
2013

Mixed-Reality Simulation for Neurosurgical Procedures
Neurosurgery
2013

Magnetic Resonance Imaging Assessment of Cerebral Arteriovenous Malformation Obliteration After Stereotactic Radiosurgery
Neurosurgery
2013

Decreasing Ventricular Infections Through the Use of a Ventriculostomy Placement Bundle: Experience At a Single Institution Clinical Article
Journal of Neurosurgery
2013

Repeat Radiosurgery for Intracranial Arteriovenous Malformations
Neurosurgery
2012

Radiographic Response of Brain Metastasis After Linear Accelerator Radiosurgery
Stereotactic and Functional Neurosurgery
2012

A Recommendation for Training in Stereotactic Radiosurgery for Us Neurosurgery Residents
Journal of Neurosurgery-Spine
2012

Spontaneous Intracranial Hypotension: Dilemmas in Diagnosis
Neurosurgery
2011

Results of a National Neurosurgery Resident Survey On Duty Hour Regulations
Neurosurgery
2011

Radiosurgery for Arteriovenous Malformations
Neurological research
2011

Linear Accelerator Radiosurgery for Nonvestibular Schwannomas
Neurosurgery
2011

Disseminated Intravascular Coagulation During Resection of a Meningioma: Case Report
Neurosurgery
2011

Albert L. Rhoton, Jr., M.D
World Neurosurgery
2011

Validation of the Radiosurgery-Based Arteriovenous Malformation Score in a Large Linear Accelerator Radiosurgery Experience Clinical Article
Journal of Neurosurgery-Spine
2009

The surgical treatment of trigeminal neuralgia: overview and experience at the University of Florida.
Journal of Neuroscience Nursing
2009

The Surgical Treatment of Trigeminal Neuralgia: Overview and Experience At the University of Florida
Journal of Neuroscience Nursing
2009

Stereotactic Radiosurgery and the Linear Accelerator: Accelerating Electrons in Neurosurgery
Neurosurgical Focus
2009

Rapid fabrication of custom patient biopsy guides.
Journal of Applied Clinical Medical Physics
2009

Rapid Fabrication of Custom Patient Biopsy Guides
Journal of Applied Clinical Medical Physics
2009

Outcomes of Who Grade I Meningiomas Receiving Radiotherapy Alone Or After Subtotal Resection
International Journal Of Radiation Oncology Biology Physics
2009

Nucleus Caudalis Dorsal Root Entry Zone Lesions: a Clinical-Radiographic Case Report
Stereotactic and Functional Neurosurgery
2009

Linear Accelerator Radiosurgery for Cavernous Sinus Meningiomas
Stereotactic and Functional Neurosurgery
2009

Hyponatremia in Neurosurgical Patients: Clinical Guidelines Development
Neurosurgery
2009

Linear accelerator radiosurgery for vestibular schwannomas.
Progress in neurological surgery
2008

Linear Accelerator Stereotactic Radiosurgery for Metastatic Brain Tumors: 17 Years of Experience At the University of Florida
Neurosurgery
2008

Do Brain Tumor Self-Rated Karnofsky Peformance Status Scores Correlate With Physician-Rated Scores?
Neuro-Oncology
2008

Can Standard Magnetic Resonance Imaging Reliably Distinguish Recurrent Tumor From Radiation Necrosis After Radiosurgery for Brain Metastases? a Radiographic-Pathological Study
Neurosurgery
2008

Pontine atypical neurocytoma: case report
Neurosurgery
2006

Linear accelerator radiosurgery for vestibular schwannomas.
Journal of Neurosurgery-Spine
2006

An investigation of the potential of rapid prototyping technology for image guided surgery.
Journal of Applied Clinical Medical Physics
2006

Linear accelerator surgery for meningiomas.
Journal of Neurosurgery-Spine
2005

Resident duty hours in American neurosurgery.
Neurosurgery
2004

Management of benign skull base meningiomas: a review.
Skull Base
2004

Magnetic resonance imaging of the posterior columns in vitamin B12 deficiency.
Archives of Neurology
2004

Salvage retreatment after failure of radiosurgery in patients with arteriovenous malformations
Journal of Neurosurgery
2003

Radiotherapy alone or after subtotal resection for benign skull base meningiomas.

2003

Mental object rotation in Parkinson's disease.
Journal of the International Neuropsychological Society
2003

Linear accelerator-based radiosurgery for vestibular schwannoma.
Neurosurgical Focus
2003

Analysis of factors predictive of success or complications in arteriovenous malformation radiosurgery.
Neurosurgery
2003

Emotional conversations in Parkinson's disease.

2001

Calibration of three-dimensional ultrasound images for image-guided radiation therapy.
Physics in medicine and biology
2001

A neuropsychological outcome study of a child's left pericallosal arteriovenous malformation with occult fornix lesion.
Neurocase
2001

Linear accelerator radiosurgery in the management of brain tumours.
Annals of Medicine
2000

Cognitive and vestibulo-proprioceptive components of spatial ability in Parkinson's disease.
Neuropsychologia
2000

Changes in vocal intensity in Parkinson's disease following pallidotomy surgery.

2000

Voice and speech characteristics of persons with Parkinson's disease pre- and post-pallidotomy surgery: preliminary findings.
Journal of speech, language, and hearing research : JSLHR
1999

Image registration of BANG gel dose maps for quantitative dosimetry verification.
International Journal Of Radiation Oncology Biology Physics
1999

Analytic characterization of linear accelerator radiosurgery dose distributions for fast optimization.
Physics in medicine and biology
1999

The radiobiology of radiosurgery and stereotactic radiotherapy.
Medical Dosimetry
1998

The effect of LINAC stereotactic radiosurgery on epilepsy associated with arteriovenous malformations.
Stereotactic and Functional Neurosurgery
1998

Potential clinical efficacy of intensity-modulated conformal therapy.
International Journal Of Radiation Oncology Biology Physics
1998

Optic-guided stereotactic radiotherapy.
Medical Dosimetry
1998

Linac scalpel radiosurgery at the University of Florida.
Medical Dosimetry
1998

Research Interests

In 1986, Friedman began collaborative work with Francis J. Bova, Ph.D., which led to the development of the patented UF radiosurgery system. The system, known as LINAC Scalpel, assists with localizing, planning and treating intracranial tumors using computer software and a specially designed linear accelerator. The LINAC Scalpel has become one of the most popular commercial radiosurgery systems worldwide and has improved the accuracy of high-dose radiation delivered to brain tumors, with very little of the dose reaching normal brain structures. Friedman and Bova received the 1990 UF College of Medicine Clinical Research Prize in recognition of this accomplishment. Friedman is the leader of a multidisciplinary radiosurgery team, which has treated more than 4600 patients, published more than 175 papers and chapters, produced many international meetings and educated hundreds of visiting physicians.