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Liver Disease
Definition
The term "liver disease" applies to many conditions that stop the liver from working or prevent it from functioning well. Abdominal pain or swelling, yellowing of the skin or eyes (jaundice), or abnormal results of liver function tests may suggest you have liver disease.
Related topics include:
- Alpha-1 anti-trypsin deficiency
- Amebic liver abscess
- Autoimmune hepatitis
- Biliary atresia
- Cirrhosis
- Coccidioidomycosis
- Delta virus (hepatitis D)
- Drug-induced cholestasis
- Nonalcoholic fatty liver disease
- Hemochromatosis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Liver disease due to alcohol
- Primary biliary cirrhosis
- Pyogenic liver abscess
- Reye syndrome
- Sclerosing cholangitis
- Wilson disease
Gallery
References
Martin P. Approach to the patient with liver disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 137.
Williams MJ, Gordon-Walker TT. Hepatology. In: Penman ID, Ralston SH, Strachan MWJ, Hobson RP, eds. Davidson's Principles and Practice of Medicine. 24th ed. Philadelphia, PA: Elsevier; 2023:chap 24.
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Clinical trials: Liver Disease
UF Health research scientists make medicine better every day. They discover new ways to help people by running clinical trials. When you join a clinical trial, you can get advanced medical care. Sometimes years before it's available everywhere. You can also help make medicine better for everyone else. If you'd like to learn more about clinical trials, visit our clinical trials page. Or click one of the links below:
The main aim of this study is to learn if fazirsiran is safe during long-term use in people with liver disease caused by the abnormal Z-alpha-1 antitrypsin (Z-AAT) protein. People who have taken part in previous fazirsiran studies (AROAAT2001…
- Investigator
- Ginger Clark
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
News and patient stories: Liver Disease
Study finds hidden blood mutations spark obesity, diabetes and liver disease
October 13, 2025
GAINESVILLE, Fla. — UF Health Cancer Center researchers have found a surprising culprit behind common health problems like obesity, diabetes and fatty liver…
Department of Pharmacology and Therapeutics, +4 more
New report recommends liver screening for those with Type 2 diabetes
June 25, 2025
GAINESVILLE, Fla. — Anyone with diabetes quickly learns the importance of controlling their blood sugar to ensure their eyes, kidneys, heart and peripheral…
Clinical and Translational Science Institute, College of Medicine, +1 more
Latest podcast episodes
Blood tests can catch liver disease before symptoms
Of the human body’s many organs, the liver is arguably one of the hardest workers. This 3-pound whirlwind in the upper right abdomen handles 500 jobs, including filtering more than 250 gallons of...
Daily sugary drinks bring higher risk for liver cancer, disease for women
You’re heading home after work and pull into a drive-thru, ordering a crisp, sweet drink to offset your headache while you steel yourself for rush hour traffic. Whether your beverage of choice is...
Sleep behaviors may affect risk of developing liver disease
Calling all night owls, afternoon snoozers and chronic snorers: When combined with a sedentary lifestyle, these circadian eccentricities could result in fatty liver disease. A study published in...